Drug Deals - BiopharmaDirect

Drug Deals

Drug Deals

Therapeutic Area  Licensor Licensee Molecule NMEs type Target Stage(then)  Stage(now)  Product Differentiation  Year Of Deal  Up-Front
CNS Alectos Merck&Co MK-8719 small molecule O-GlcNAcase Phase I Phase I FIC 2010 $289 Mn
chronic kidney disease Reata Abbott bardoxolone small molecule Nrf2 Phase II Phase III FIC 2010 $450 Mn
oncology Pharmacyclics Janssen   PCI-32765 small molecule BTK Phase II approved FIC 2011 $150 Mn
Acute Kidney Injury  Action Abbott AP214 Biologic melanocortin peptide agonist Phase II Phase II FIC 2012 $110 Mn
Inflammation and Autoimmune diseases Ablynx AbbVie ALX-0061 Biologic IL-6R Phase II Phase II best in class 2013 $175 Mn
Anemia FibroGen AstraZeneca FG-4592 small molecule HIF Phase II approved FIC 2013 $315 Mn
IInflammation and Autoimmune diseases  Nogra Celgene GED-0301 Biologic Smad7 Phase II Terminated FIC 2014 $710 Mn
endocrine disease OPKO Pfizer hGH-CTP Biologic hGH Phase III ongoing best in class 2014 $295 Mn
oncology Regeneron Sanofi cemiplimab Biologic PD1 Phase I approved Me too 2015 $650 Mn
Diabetes Hanmi Sanofi efpeglenatide Biologic GLP1 Phase II Terminated Me too 2015 $422 Mn
Diabetes Lexicon Sanofi Zynquista small molecule SGLT1/SGLT2 Phase II approved FIC 2015 $300 Mn
CNS Merck Allergan MK-1062 small molecule CGRP Phase II Phase II FIC 2015 $125 Mn
oncology MedImmune Celgene  MEDI4736 Biologic PD-L1 Phase III approved FIC 2015 $450 Mn
Diabetes Hanmi Johnson & Johnson HM1252A Biologic GLP-1/Glucagon Phase I Phase II failure FIC 2015 $105 Mn
Inflammation and Autoimmune diseases Galapagos NV Gilead filgotinib small molecule JAK1 Phase II Phase III FIC 2015 $725 Mn
oncology Xencor Novartis XmAb14045 Biologic CD123-CD3 discovery FIC 2016 $150 Mn
NASH Nitto BMS ND-L02-s0201 Biologic HSP47 Phase I FIC 2016 $100 Mn
oncology Beigene Celgene BGB-A317 Biologic PD1 Phase I Me too 2017 $263 Mn
oncology Legend Jassen LCAR-B38M Biologic BCMA Phase I FIC 2017 $350 Mn
CNS BMS Biogen BMS-986168 Biologic tau Phase I FIC 2017 $289 Mn

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